Grid Control manages the Lot

Ray Payne,  Principal Architect, Oracle Infrastructure at The Johns Hopkins Applied Physics Laboratory, mentioned in an answer to a LinkedIn question: 

We are finding that Oracle Enterprise Manager Grid Control and various management packs and plug-ins are pretty comprehensive. We are using for Database, Operating System, Middleware, Applications (EBusiness Suite and Peoplesoft), as well as our EMC Storage and F5 BigIP load balancers. Comprehensive, and all in one tool supported by one vendor. 

I fully support and second what Ray has said. Grid Control indeed manages the lot.